Samtools Stack Overflow Spectacle: How Huge Histograms Can Crash Your Day!
Beware of bin overload! Samtools v1.22.1 has a bit of a meltdown when handling excessive histogram bin counts, leading to a stack overflow. Just one giant bin count can turn your coverage calculations into a comedy of errors and crash the program. Remember, in the world of bins, bigger isn’t always better!

Hot Take:
Looks like Samtools just tried to fit an elephant through a mouse hole and ended up with a stack overflow! When it comes to handling excessive histogram bins, Samtools’ coverage subcommand is clearly not a fan of going big or going home. Instead, it just crashes and burns. Maybe they should stick to counting sheep instead of bins!
Key Points:
- The issue arises in Samtools’ coverage subcommand due to improper handling of excessive histogram bin counts.
- Using an extremely large number of bins can lead to integer division errors, unexpected behavior, and ultimately a stack overflow.
- The vulnerability can result in a Denial of Service (DoS) or memory corruption.
- A proof of concept shows that using a massive bin count can crash the program.
- The crash is confirmed by an AddressSanitizer error indicating a stack overflow.
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