DNA Sequencers at Risk: Outdated Firmware Makes Illumina iSeq 100 a Cybersecurity Comedy of Errors
The Illumina iSeq 100 DNA sequencer’s outdated BIOS firmware is a cybercriminal’s dream come true. Vulnerable to attacks that could brick the device or plant malware, it’s like leaving your front door wide open with a welcome mat for hackers. Illumina has released a fix—time to update, unless you’re into living dangerously.

Hot Take:
When your DNA sequencer is stuck in the past, you might end up with a firmware horror story that’s scarier than any sci-fi movie. Who knew that the Compatibility Support Mode could be a time machine to vulnerabilities? It seems like the iSeq 100 is a little too nostalgic for the 2018 BIOS era. Is it time for a firmware intervention? You betcha!
Key Points:
- Illumina iSeq 100 DNA sequencers are vulnerable due to outdated BIOS firmware.
- Lack of Secure Boot and firmware write protections allow potential attacks.
- Eclypsium highlights the risks of Compatibility Support Mode (CSM) in modern devices.
- Previous vulnerabilities in Illumina devices include high-severity network flaws.
- Fix released post-responsible disclosure, but risks remain for unpatched devices.
Already a member? Log in here